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Vampire Survivors – The Best Weapon Combinations to Use

Authore: ConnorUpdate:Feb 21,2025

Unleash the deadliest weapon combos in Vampire Survivors! This guide unveils the most effective weapon pairings for maximum damage and efficiency. For roguelike RPG fans, Vampire Survivors offers a unique bullet-hell experience. You control your character's movement, dodging and letting equipped weapons handle the attacks. Multiple DLCs have expanded the arsenal, creating powerful combinations. Let's dive into the top pairings!

Prism Lass + Glass Fandango


Prism Lass

  • Base Damage: 10
  • Max Level: 8
  • Evolves with Wings
  • Circles the character when evolved

Glass Fandango

  • Base Damage: 10
  • Max Level: 8
  • Increased damage against frozen enemies
  • Evolves with Wings

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This combo utilizes a unique, targeted attack style. Unlike area-of-effect (AOE) weapons, these weapons prioritize damage per enemy, focusing on those closest to your character. The mid-game, particularly after the 20-minute mark, becomes significantly easier with this strategy. We recommend adding the King Bible as a fourth weapon; its protective barrier proves invaluable given the close-range combat required.

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